Whole-Genome Sequencing (WGS)
Explore genetic variation across coding and noncoding regions of the genome.
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Explore genetic variation across coding and noncoding regions of the genome.
Focus sequencing on exonic regions to investigate variants affecting protein-coding genes.
Measure gene and transcript expression to investigate differential expression, alternative splicing and biological pathways.
Resolve cell populations, expression heterogeneity and cell states at single-cell resolution.
Profile full-length transcripts from single cells or very small amounts of RNA using template-switching amplification.
Map open chromatin with Tn5 transposase and compare chromatin accessibility across conditions.
Map transcription factor binding and histone modifications by sequencing DNA enriched with a target-specific antibody.
Profile chromatin-associated proteins using antibody-directed Tn5 tagmentation.
Profile DNA methylation across the genome at single-base resolution using bisulfite conversion and sequencing.
Profile DNA methylation in CpG-rich regions with lower sequencing requirements.
Compare regional DNA methylation patterns using antibody enrichment of methylated DNA.
Map m6A-enriched RNA regions and compare RNA methylation patterns across the transcriptome.
Identify RNAs associated with a protein of interest through RNA immunoprecipitation and sequencing.
Map RNA-binding protein interaction regions and sequence preferences using crosslinking, immunoprecipitation and sequencing.
Profile selected tissue regions while retaining their spatial context through laser capture microdissection.
Map chromatin contacts to investigate three-dimensional genome organization and its changes across conditions.
Connect transcriptomic, chromatin and DNA methylation data to investigate gene regulation across sequencing assays.
Identify and quantify proteins by mass spectrometry to compare protein composition and abundance.
Compare metabolic profiles or quantify selected metabolites to investigate biological and treatment-related changes.
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