Targeted & Untargeted Metabolomics

How it works

Untargeted metabolomics compares metabolic profiles across study groups to identify metabolites for follow-up. Targeted metabolomics focuses on defined metabolites, using reference standards for quantification. We help select a discovery or validation approach based on the research question.

Applications

• Investigate metabolic changes associated with disease, drug treatment or environmental stimuli
• Discover metabolites of interest and assess them through targeted analysis
• Study metabolism in plants, microorganisms, food and other biological systems

Key features

• Untargeted profiling for broad metabolite discovery
• Targeted quantification of predefined metabolites
• Integration with other omics data for pathway interpretation

Workflow

1. 01

   Define the discovery or targeted quantification objectives

2. 02

   Prepare samples, extract metabolites and perform quality control

3. 03

   Analyze samples by an appropriate chromatography-mass spectrometry method

4. 04

   Annotate or quantify metabolites and analyze differences and pathways

We tailor the experimental workflow and analysis to your samples and study objectives.